The patient was admitted to our department 9 months after anterior cruciate ligament (ACL) reconstruction with pain and limitation of full extension.
A patient with ACL reconstruction, presented with inability to full knee extension and pain when attempts were made.
The ACL graft is intact with homogeneous low signal and anterior to the graft a nodular soft tissue mass with intermediate signal intensity, outlined by fluid, with 12mm diameter was seen. The ACL graft tunnel in the tibia is a little too far back.
Because of its ability to define bony and soft tissue detail, MR imaging can be used to examine patients with extension loss after ACL reconstruction [1] MR imaging can be used to demonstrate graft failure, graft impingement, and arthrofibrosis [2].
The presence of primary impingement leading to graft injury and secondary formation of cyclops lesion may be the cause of increased signal intensity in ACL grafts [1]. Graft impingement is a complication that can occur with an ACL graft when the graft abuts the roof or wall of the intercondylar notch. This complication is associated with anterior placement of the tibial tunnel, osteophytes at the margins of the intercondylar notch, and small intercondylar notch [2].
To avoid impingement, the anterior edge of the tibial tunnel must lie behind the projection of a line through the intercondylar roof in the sagittal plane with the knee fully extended [1]. In our patient, the tibial tunnel did not extend anterior to this projection of the intercondylar roof and the ACL graft showed homogeneous low signal intensity.
A localized form of anterior arthrofibrosis, the so-called Cyclops lesion [4] is a nodular structure consisting of fibrous granulation tissue located anterior along the ACL graft. This nodule becomes trapped between the femur and tibia when the knee is extended and leads to a mechanical block of terminal extension. Patients with extension loss caused by cyclops lesions require second arthroscopy to resect the nodule. Cyclops lesion may originate from a residual tibial ACL stump, a tibial tunnel trapdoor, infrapatellar fat pad metaplasia, intercondylar fibrosis, or the graft itself.
Research shows evolution of the cyclops lesion progressing from early fibrosis to fibrocartilage. Tissues that may contribute to the formation of cyclops lesion include fibrous tissue, fibrocartilage, bone, synovium, and fat from the infrapatellar fat pad [1].
Fibrous lesions usually have low signal intensity on MR images, but cyclops lesions have higher signal intensity than is typically seen in fibrous lesions, likely due to irritation of the lesion because it is pinched between the two bones. Conventional MR imaging was shown to be 85% accurate for detection of localized anterior arthrofibrosis in one study [1]. That study showed higher accuracy for detection of lesions that are greater that 10mm in at least one dimension.
Because of its ability to define bony and soft-tissue detail, MR imaging provides a non-invasive method of detecting cyclops lesions and helps to identify patients who need a second arthroscopy.
Cyclops Lesion
Based on the patient’s complaint of flexion-extension difficulties and inability to fully extend the knee at 9 months post-surgery, combined with a history of anterior cruciate ligament (ACL) reconstruction, the MRI examination of the knee shows the following main features:
Based on the imaging findings and clinical history, the following diagnoses or differential diagnoses are considered:
Considering the limitation in knee extension 9 months post-surgery, the nodular fibrous proliferative lesion noted on the anterior aspect of the joint on MRI, and the common presentation of a “Cyclops lesion” after ACL reconstruction leading to mechanical extension block, the most likely diagnosis is:
“Cyclops lesion” (focal anterior joint fibroproliferation)
If there is still diagnostic uncertainty, arthroscopic evaluation for direct visualization and possible lesion resection can be considered.
This report is a reference analysis based on current imaging and clinical information, and cannot replace an in-person consultation or professional physician assessment. Specific diagnosis and treatment should be conducted by a qualified clinician, taking into account the patient’s actual condition.
Cyclops Lesion