Benign osteoblastoma of occipital bone

Clinical Cases 03.06.2010
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Section: Musculoskeletal system
Case Type: Clinical Cases
Patient: 14 years, male
Authors: Gokalp G, Yalcinkaya U, Yildirim N, Yazici Z
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Clinical History

A 14-year-old boy was referred for evaluation of head and neck pain.

Imaging Findings

A 14-year-old boy was referred for right neck and occipital region pain worsening during the last eight months. Family history and neurological examination were insignificant. Plain X-ray films demonstrated an osteolytic mass surrounded by a sclerotic rim within the diploic space. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a 55x48x37 mm expansile posterior fossa mass within occipital bone protruding into right cerebellar hemisphere and fourth ventricle and also extending to muscles inferiorly. The lesion was well-circumscribed and contained calcifications.

The mass was iso-hypointense on T1-weighted, T2-weighted and FLAIR images and showed significant homogenous enhancement after contrast material adminstration. It also narrowed posterior portion of foramen magnum. Fourth ventricle was compressed and both lateral ventricles and third ventricle showed mild dilatation (Fig 1-4). Osteoblastoma was the definitive diagnosis after histopathological evaluation (Fig 5).

Discussion

Osteoblastoma was initially defined by Jaffe and Lichtenstein in 1956 [1]. It is also known as giant osteoid osteoma and its diameter exceeds fifteen centimeters. It is usually encountered in adolescents or young adults, more often in males [2, 3]. It is a rare osteoid derived, solitary, vascular benign bone tumour usually involving vertebrae and long bones of lower extremity [1-4]. Calvarium is occasionally affected and temporal and frontal bones are mostly involved while occipital bone involement is the rarest form [1, 5]. Clinical symptoms are non-specific and may involve pain or painful mass [2].

Radiological features are non-specific and depend on the stage and presentation time. Clinical, radiological and histopathological findings are needed for the definitive diagosis. It may present with osteolytic, blastic or mixed pattern [1-5].

Well-circumscribed lytic lesions surrounded with minimal sclerosis originating from medullar portion of the bone are depicted with radiography [5, 6]. Despite its benign nature, it may show local recurrence or malignant transformation [7-9].

CT and MRI are proved to be effective for the evaluation of the intracranial and intraosseous extensions of the tumour [2, 5]. Signal intensities of osteoblastomas vary in different reports of MRI characteristics [10-12]. They may also show none or significant enhancement following contrast material adminstration [10-12]. MRI is more valuable than CT in demonstrating intracranial extentions [5].

The differential diagnosis includes aneurysmal bone cyst or giant cell tumour causing remodeling and expansion. Homogenous, dense foci within the tumour suggest osteoid nature and can aid in differential diagnosis. Epidermoid and dermoid cysts, intradiploic meningioma and eosinofilic granuloma are other occipital region tumours. Definitive diagnosis is established with clinical, radiological and histopathological findings [5].

Radiological evaluation is valuable for the rarely seen osteoblastoma of occipital bone. Preoperative demonstration of local tumour extension is critical for this lesion with the propensity of local recurrence and consecutive malignant transformation.

Differential Diagnosis List

Occipital osteoblastoma

Final Diagnosis

Occipital osteoblastoma

Liscense

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