A 14-year-old boy was referred for evaluation of head and neck pain.
A 14-year-old boy was referred for right neck and occipital region pain worsening during the last eight months. Family history and neurological examination were insignificant. Plain X-ray films demonstrated an osteolytic mass surrounded by a sclerotic rim within the diploic space. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a 55x48x37 mm expansile posterior fossa mass within occipital bone protruding into right cerebellar hemisphere and fourth ventricle and also extending to muscles inferiorly. The lesion was well-circumscribed and contained calcifications.
The mass was iso-hypointense on T1-weighted, T2-weighted and FLAIR images and showed significant homogenous enhancement after contrast material adminstration. It also narrowed posterior portion of foramen magnum. Fourth ventricle was compressed and both lateral ventricles and third ventricle showed mild dilatation (Fig 1-4). Osteoblastoma was the definitive diagnosis after histopathological evaluation (Fig 5).
Osteoblastoma was initially defined by Jaffe and Lichtenstein in 1956 [1]. It is also known as giant osteoid osteoma and its diameter exceeds fifteen centimeters. It is usually encountered in adolescents or young adults, more often in males [2, 3]. It is a rare osteoid derived, solitary, vascular benign bone tumour usually involving vertebrae and long bones of lower extremity [1-4]. Calvarium is occasionally affected and temporal and frontal bones are mostly involved while occipital bone involement is the rarest form [1, 5]. Clinical symptoms are non-specific and may involve pain or painful mass [2].
Radiological features are non-specific and depend on the stage and presentation time. Clinical, radiological and histopathological findings are needed for the definitive diagosis. It may present with osteolytic, blastic or mixed pattern [1-5].
Well-circumscribed lytic lesions surrounded with minimal sclerosis originating from medullar portion of the bone are depicted with radiography [5, 6]. Despite its benign nature, it may show local recurrence or malignant transformation [7-9].
CT and MRI are proved to be effective for the evaluation of the intracranial and intraosseous extensions of the tumour [2, 5]. Signal intensities of osteoblastomas vary in different reports of MRI characteristics [10-12]. They may also show none or significant enhancement following contrast material adminstration [10-12]. MRI is more valuable than CT in demonstrating intracranial extentions [5].
The differential diagnosis includes aneurysmal bone cyst or giant cell tumour causing remodeling and expansion. Homogenous, dense foci within the tumour suggest osteoid nature and can aid in differential diagnosis. Epidermoid and dermoid cysts, intradiploic meningioma and eosinofilic granuloma are other occipital region tumours. Definitive diagnosis is established with clinical, radiological and histopathological findings [5].
Radiological evaluation is valuable for the rarely seen osteoblastoma of occipital bone. Preoperative demonstration of local tumour extension is critical for this lesion with the propensity of local recurrence and consecutive malignant transformation.
Occipital osteoblastoma
Based on the provided CT and MRI images, a relatively well-defined lesion showing bone destruction and expansion is observed in the occipital bone region, with relatively clear margins. On CT, the lesion appears lytic, and mild sclerotic changes can be seen in some areas. On MRI, the lesion shows iso- or hypointensity on T1-weighted images and heterogeneous or slightly hyperintense signals on T2-weighted images. Contrast enhancement reveals varying degrees of enhancement, indicating a rich blood supply. Part of the lesion protrudes into the cranial cavity but still maintains a certain boundary with the surrounding brain tissue. No significant compression or cerebral edema is observed in the parenchyma, and the basal cisterns, brainstem, and nearby soft tissues remain relatively intact in shape.
Combining the patient’s gender (male), age (14 years), and the occipital location of the lesion with local pain as the main symptom, possible differential diagnoses include:
Combining the patient’s age, clinical symptoms (persistent head and neck pain), imaging characteristics (lytic lesion in the occipital bone with partial sclerotic margins and variable enhancement on MRI), and histological findings demonstrating osteoid formation and osteoblast proliferation, the most likely final diagnosis is occipital osteoblastoma.
1. Treatment Strategy:
2. Rehabilitation and Exercise Prescription:
Throughout the rehabilitation process, follow the FITT-VP Principle (Frequency, Intensity, Time, Type, Volume, Progression). Progress should be guided by a professional physician or rehabilitation therapist, ensuring bone stability and healing are adequately monitored to prevent complications from premature loading.
This report is a reference based on the currently available information and does not replace in-person consultations or professional medical advice. If you have further questions or develop new symptoms, please seek timely medical attention and consult with a qualified healthcare professional.
Occipital osteoblastoma