A 10-year-old boy presents to the Emergency Department with acute and spontaneous pain in the left hip, after playing a football-game.
At clinical examination, there was focal tenderness around the greater trochanter and pain at flexion and rotation of the hip.
On conventional radiographs of the hip, a well-circumscribed, radiolucent lesion was seen in the central metaphysis of the femur, without periosteal reaction. The lesion appeared multilocular and was described as "soap-bubble"-like.
Subsequent magnetic resonance imaging (MRI), revealed the lesion to be of high signal intensity on fat suppressed T2-weighted images (WI) and isointense to muscle on T1-WI.
After intravenous administration of gadolinium, peripheral rim-enhancement was seen, whereas the central part of the lesion was not enhancing. Sagittal images showed no fluid/fluid levels.
Based on these findings, the diagnosis of a Solitary Bone Cyst was made.
Because no pathologic fracture was seen, the patient’s pain was attributed to muscle contusion and the patient was initially treated with pain relievers and relative rest.
Because of the increased fracture risk due to the cortical thinning, a dynamic hip screw was placed.
Solitary bone cysts (SBC) are defined as "tumour-like lesions of unknown etiology, attributed to local disturbance of bone growth" [1].
Because SBC’s occur in patients whose growth plates are not yet or recently closed, patients are young (85% <20 years old) [2].
The lesions are usually located in the central metaphysis of long bones, most often the proximal humerus or femur, although a wide variety of locations has been described. Involvement of the calcaneus and/or ilium occurs in adult patients [1, 3].
Uncomplicated SBC's are merely asymptomatic, but occasionally, pain or stiffness may be present in the adjacent joint.
Large lesions are at risk for pathologic fracture through the cyst, and some patients present with acute pain following these fractures [1].
On conventional radiographs, SBC's present as well-circumscribed, radiolucent lesions in the central metaphysis. Their long axis parallels the long axis of the affected bone.
They can appear multilocular on plain films, due to projection of the ridging of the walls of the cyst (pseudotrabeculation) but are macroscopically always unicameral.
After a pathologic fracture, small bony fragments may migrate through the fluid-filled cavity and create a pathognomonic 'fallen fragment sign': a fragment of cortical bone attached to the periosteum or lying in the dependent part of the lesion [3-5].
On MR-imaging, SBC's show the typical features of cysts, i.e. high signal intensity on T2-WI and low on T1-WI. After intravenous gadolinium-administration , a thin rim of peripheral enhancement is seen [5].
When a fracture has occurred, signal intensity on T2-WI may become heterogeneous, due to intralesional bleeding.
The most important differential diagnoses are [1]:
- Aneurysmal bone cysts: more eccentric located, fluid/fluid-levels on T2-WI.
- Fibrous dysplasia: ‘ground glass’ appearance on radiographs, variable appearance on MR-imaging (MRI does not provide additional information).
- Brodie abscess: causes severe pain, surrounding bone marrow oedema on MRI.
- Giant cell tumours: adult patients, juxta-articular location, heterogeneous intensity on T2- and T1+Gd –WI.
Asymptomatic SBC’s require no treatment and regress spontaneously after closing of the growth plates.
Occasionally, treatment is advocated due to risk of pathologic fracture. The most accurate predictor of fractures is the Bone Cyst Index (BCI). SBC's with BCI larger than 3.5 (femur) or 4 (humerus) are at risk for pathologic fracture. Size of the lesion and cortical thinning are poorly correlated with fracture-risk. [6]
Possible treatments include curettage, corticoid injection, bone grafting or DHS placement (proximal femur).
Cysts that are complicated by a pathologic fracture usually regress during healing of the fracture.
Solitary/Unicameral/Juvenile Bone Cyst (SBC)
The patient is a 10-year-old boy who developed acute, spontaneous pain in the left hip region after physical activity. Based on the provided imaging data (including X-ray and MRI), a notable cystic lesion is observed in the left proximal femur (near the trochanteric region):
Based on the patient’s age, imaging findings, and clinical presentation, the following diagnoses or differential diagnoses are considered:
Considering the patient’s age, pain characteristics, and imaging findings (a single-chamber cystic radiolucent area, thin rim enhancement, located in the proximal femur near the trochanteric region), the most likely diagnosis is a Solitary Bone Cyst (SBC).
If subsequent imaging follow-up or pathological examination confirms these features, the diagnosis can be definitively established.
A gradual rehabilitation program based on the FITT-VP principle is recommended, tailored to the type of surgery or conservative treatment:
Throughout the rehabilitation process, special attention should be paid to the growth characteristics of the child’s bones and overall bone health. Avoid strong impacts or excessive weight-bearing that may increase the risk of recurrent fractures. Regular imaging follow-up is recommended to evaluate any changes in the cyst and monitor bone healing.
Disclaimer: This report provides a reference for medical imaging analysis and does not replace in-person consultation or professional medical advice. Specific treatment plans should be individualized according to the patient’s actual condition under the guidance of a specialist.
Solitary/Unicameral/Juvenile Bone Cyst (SBC)