A 50-year-old female patient presented with low back pain for 3 months. She had experienced difficulty in standing up from sitting position for 15 days. She had associated complains of low-grade fever and weight loss for 3-4 months. The patient was referred for MRI of the lumbosacral spine.
CT shows end plate irregularity and sclerosis of L3 and L4 vertebral bodies with decreased height of intervening L3-L4 intervertebral disc (Fig. 1, 2).
MRI shows irregularity and destruction of L3-L4 end plates and intervertebral disc with well-defined collection in the prevertebral and bilateral paravartebral regions (Fig. 5, 6) which appears hypointense on T1W (Fig. 3, 5) and hyperintense on T2W (Fig. 4, 6). The collection is seen extending in the left psoas muscle leading to psoas abscess (Fig. 6). A small epidural collection is seen at the level of L3 and L4 vertebrae which is causing compression over the spinal cord (Fig. 4b).
Musculoskeletal involvement of TB is estimated in 1–13 % of patients and spine is affected in more than 50% of cases. “Pott’s Disease” (tuberculous spondylitis) represents the most common form of extrapulmonary TB. The thoracic segments are the preferred sites, followed by the lumbar levels. Pott's spine involves two contiguous vertebral bodies with the intervening disk, but multilevel extension (three or more vertebrae) characterizes the disease[1].The paradiscal, central, anterior subligamentous, and neural arch are the common vertebral lesions. In Pott's spine, the onset of symptoms is usually insidious and progression is slow.
In the paradiscal type, the earliest features are narrowing of the joint space and indistinct paradiscal margin of vertebral bodies. With further progression, anterior wedging or collapse occurs, resulting in varying degree of kyphosis.
In the anterior type of the lesion, the collection of tuberculous granulation tissue and necrotic material leads to formation of paravertebral abscess which is visible on plain radiographs as a fusiform radiodense shadow called the bird nest appearance. Long standing abscesses may produce concave erosions around the anterior margins of the vertebral bodies producing a scalloped appearance called the aneurysmal phenomenon (gouge defect).
The central type of the lesion presents as destruction, ballooning of vertebral bodies, and concentric collapse.
In the neural arch type of the lesion, there is involvement of the posterior arches (spinous process, lamina, pedicle, and transverse process as well as lateral masses of the atlas), pedicular or laminar destruction, erosion of the adjacent ribs in the thoracic region or posterior cortex of the vertebral body with relative sparing of the intervertebral discs, and a large paraspinal mass.
The pattern of bone destruction (fragmentary, osteolytic, sclerotic, and subperiosteal) can be seen well on CT. The presence of calcification within the abscess is virtually diagnostic of spinal TB [2]. Most cases of the active disease have paraspinal (subligamentous, psoas, epidural) soft tissue masses [3]. MRI features of Pott's spine appear hypointense on T1W and hyperintense on T2W sequences with heterogeneous enhancement of the vertebral body. STIR sequences are helpful in differentiating fluid from fatty components in non-contrast sequences. Administration of Gd-DTPA is useful to assess the extent of soft tissue mass. Kyphosis and cord compressions are the most common complications [2].
Treatment with antituberculous medications with surgical debridement and reconstruction of spinal stability are the key aspects [4].
It is often difficult to differentiate between tuberculous and pyogenic spondylitis, both clinically and on images. When infection is suspected, a history of chronicity and insidious progression is suggestive of tuberculous spondylitis [5].
Pott's spine with psoas abscess
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Based on the provided lumbar spine CT and MRI images, the following main features are observed:
Considering the patient’s chronic lower back pain, low-grade fever, weight loss, and the imaging characteristics noted above, the following diagnoses should be considered:
Based on the patient’s:
The most likely diagnosis is Tuberculous Spondylitis (Pott’s Disease). For definitive confirmation, it is recommended to perform further laboratory tests (such as T-SPOT.TB, tuberculin skin test, serological evaluations) or conduct a biopsy of the lesion to confirm the pathogenic organism if necessary.
Rehabilitation should be conducted under the guidance of healthcare professionals and physical therapists, starting from low intensity and progressing gradually:
Throughout this process, special attention should be paid to bone fragility and overall physical condition. Proper technique and safety must be ensured.
This report provides a reference analysis based on the patient’s imaging and basic clinical information. It is not a substitute for an in-person clinical diagnosis or professional medical advice. For specific treatment decisions, please follow the guidance of a specialist and the results of further examinations.
Pott's spine with psoas abscess
