Unstable juvenile osteochondritis dissecans with displaced fragment

Clinical Cases 08.04.2020
Scan Image
Section: Musculoskeletal system
Case Type: Clinical Cases
Patient: 14 years, female
Authors: Clara Morandeira Arrizabalaga, Dagmar Kempink, Monique Reijnierse
icon
Details
icon
AI Report

Clinical History

14-year-old girl with previous history of oligoarthritis treated with methotrexate. She presented with chronic pain in the left knee. However, during the past month, the pain had increased and was accompanied by a sudden motion restriction while walking.

Imaging Findings

The anteroposterior and lateral radiographs of the knee showed a crescentic lucency in the medial condyle articular surface of the femur with surrounding sclerotic foci.

In the MRI examination, DP Dixon in axial, coronal and sagittal sequences were performed. The curved hypodensity correlates with a fracture line extending through the cartilage and subchondral endplate with surrounding subchondral cysts. In the anterior part, the fluid sequence depicts a low signal rim with surrounding oedema of the lesion. In the posterior area, there is a subchondral fluid- filled defect. In the suprapatellar space, there is a free body, with bone and cartilage content.

After the diagnoses, surgery was performed and radiological findings were confirmed.

Discussion

Recently, there have been updates about the terminology of the osteochondral lesions of the knee. Nowadays, the term of Osteochondritis Dissecans (OCD) is the most widely used for an idiopathic fracture line extending through the articular cartilage and the underlying bone in the knee [1, 2]. Within the risk factors, repetitive trauma is accepted [1, 3].

OCD generally affects children and young people [1, 2, 4]. These patients complain about knee pain and swelling, with restricted motion in severe cases with displaced fragment bones [1, 3, 4]. In long-term follow up, the subsequent irregularity of the articular surface can lead to osteoarthritis [1, 3, 4].

CT and X-ray depict a lucent curved fracture in the articular surface, normally affecting the lateral aspect of the medial femoral condyle. In displaced cases, the lucency is focal and accompanied by an intraarticular body with variable bone maturation [1, 2].

MRI is more accurate for OCD diagnosis and can also exclude other chondral damage [1, 2]. It shows the fracture line in the cartilage and the subarticular bone endplate, with adjacent bone oedema in acute cases. In the displaced cases, we can see the bone fragment with variable bone and cartilage components.

Even if the accuracy of the lesion stability is in debate [2, 3, 4], some radiologic signs can help us to distinguish between stable and unstable cases [1, 3]. The instability signs are [1, 2, 3, 4]:

  1. high T2-signal surrounding the injury, with the same signal intensity of the joint fluid. The signal intensity must be compatible with fluid and must not be confused with granulation tissue [3]
  2. low T2-signal intensity outer rim, compatible with sclerosis
  3. multiple or large (more than 5 mm) subchondral cysts
  4. multiple subchondral breaks

Furthermore, when a displaced fragment is seen, the lesion is also considered unstable. In these patients, we can see the displaced bone fragment with variable bone and cartilage components [1].

The treatment depends on the skeletal maturation and the stability of the lesion [1, 3, 4]. In stable patients, conservative treatment is usually preferred with motion restriction and non-weight-bearing. In unstable or symptomatic cases, drilling, pinning and grafting techniques are performed to encourage vascularisation. Furthermore, excision or fixation of the bone fragments if displacement is done.

Take home message
OCD usually affects the knee in young patients. An early and accurate diagnosis is necessary to prevent long-term consequences.

Written informed patient consent for publication has been obtained.

Differential Diagnosis List

Unstable juvenile OCD with displaced fragment
Acute osteochondral fracture
Subchondral fracture
Osteoarthritis
Osteonecrosis

Final Diagnosis

Unstable juvenile OCD with displaced fragment

Figures

icon
AP (a) and lateral (b) radiographs of knee reveal a localised ossification injury in the medial condyle articular space.
icon
AP (a) and lateral (b) radiographs of knee reveal a localised ossification injury in the medial condyle articular space.

icon
Coronal DP Dixon (fluid sequence) depicts a defect line extending through the cartilage and subchondral endplate with surroun
icon
Coronal DP Dixon (fluid sequence) depicts a defect line extending through the cartilage and subchondral endplate with surroun

icon
Sagittal gradient echo exhibits multiple subchondral cysts.
icon
Sagittal gradient echo exhibits multiple subchondral cysts.

icon
Axial DP Dixon (fluid sequence) (a) and sagittal DP Dixon (in-phase) (b) show an OCD fragment displaced into the retropatella
icon
Axial DP Dixon (fluid sequence) (a) and sagittal DP Dixon (in-phase) (b) show an OCD fragment displaced into the retropatella

icon
Surgical pictures. A) and b) the free bone fragment and osteochondral defect are seen. C) The bone fragment is cleaned and re
icon
Surgical pictures. A) and b) the free bone fragment and osteochondral defect are seen. C) The bone fragment is cleaned and re
icon
Surgical pictures. A) and b) the free bone fragment and osteochondral defect are seen. C) The bone fragment is cleaned and re