A 7-year-old boy, Tae-Kwon-Do athlete, presented with insidious onset of pain and swelling of the right foot over two months, without any history of trauma. Pain initially presented during sports activities but gradually it became constant during everyday activities. Clinical examination revealed tenderness over the first metatarsal. Medical history was unremarkable.
Anteroposterior and oblique plain foot radiographs demonstrated flattening, sclerosis, without significant fragmentation of the distal first metatarsal epiphysis (Fig. 1). MR with STIR and T2-weighted (T2W) images confirmed articular collapse and necrosis of the distal epiphysis which appeared with low signal intensity surrounded by extensive high signal bone marrow oedema of the metatarsal diaphysis (Fig. 2). A subchondral linear fracture was also shown as a linear low signal intensity lesion within the bone marrow oedema.
Background
Freiberg’s disease (FD) is an idiopathic avascular necrosis located in the second metatarsal head in 2/3 of cases and the third in about 1/3 [1]. Involvement of the lesser toes and first metatarsal is extremely rare [1-3]. The pathophysiology of FD is still unclear. Vascular damage due to repetitive microtrauma and fractures of the subchondral bone may be the underlying cause [4]. FD has been linked to high-heeled shoes and its prevalence is higher in women at their second decade of life [5,6].
Clinical Perspective
Clinical examination reveals swelling and tenderness of the affected metatarsophalangeal joint. History may or may not reveal previous trauma. Disease progression leads to foot deformity with a claw or crossover toe appearance. Conservative treatment is the mainline of management, along with non-steroidal anti-inflammatory medication, activity modification and use of rocker bottom shoes. Surgical treatment is reserved only for cases of advanced disease or when conservative treatment has failed and includes a combination of debridement, loose body removal, osteotomies and core decompression [4,5]. In our case, repetitive microtrauma due to intensive Tae-Kwon-Do training was postulated to be the causative factor. Despite the atypical age, sex and location, imaging findings and clinical history were highly specific for FD.
Imaging Perspective
Plain films may demonstrate sclerosis, flattening and fragmentation of the affected metatarsal head. MRI is the imaging modality of choice since it can detect the disease at early stages when findings in plain films are absent or subtle [7]. At the initial stages, MRI shows low signal intensity of the metatarsal head on T1W and high signal intensity on fluid sensitive sequences. As necrosis evolves, the metatarsal head appears with low signal intensity on all pulse sequences. Bone marrow oedema of the surrounding bone, subchondral fracture lines and metatarsophalangeal joint effusion may also be present [1,6,7]. The disease can be classified to five stages of severity according to Smillie, which works both for plain films and MRI [5]. Surgical treatment is reserved for advanced disease.
Outcome
Conservative treatment usually provides full resolution of symptoms and imaging findings. In our case, due to the demand for return to high level of performance, the patient was treated surgically with debridement and core decompression. Complete resolution of symptoms and imaging findings were noted at the 1.5 year follow-up (Fig. 3).
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Freiberg’s disease of the first metatarsal head in a child
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The patient is a 7-year-old boy who has been experiencing pain and swelling in the area of the first metatarsal head on the right foot for about two months. The provided X-ray images show:
Regarding the MRI findings:
Overall, the imaging findings suggest avascular necrosis of the first metatarsal head, accompanied by fragmented bone structure, sclerosis, and edema signals.
Based on the patient’s age, symptoms, and imaging findings, the possible diagnoses or differential diagnoses include:
Based on the radiographic characteristics and the clinical course, Freiberg disease is strongly considered as the primary diagnosis.
Taking into account the patient’s age (even though the gender differs slightly from the typical demographic), regular physical activity (chronic microtrauma possibly from Taekwondo training), and the imaging findings (sclerosis and fragmentation of the first metatarsal head, along with significant bone marrow edema and signal alterations on MRI), the most likely diagnosis is:
Freiberg disease (avascular necrosis of the first metatarsal head).
If uncertainty remains, further clinical evaluations (laboratory inflammatory markers, tests to rule out infection or rheumatic causes) could be performed to exclude other etiologies. However, based on the current data, Freiberg disease is the most probable diagnosis.
Treatment options can be divided into conservative and surgical approaches, which should be chosen depending on the patient’s activity requirements and the severity of the lesion:
If the lesion is relatively advanced, or if conservative treatment fails to provide sufficient relief, surgical options include:
In this case, if the child has higher sporting demands and cannot achieve adequate functional recovery through conservative means, surgical intervention may be considered.
Since the patient is still young and the skeletal system is in a developmental phase, rehabilitation and exercise prescriptions must be individualized and progressive. The FITT-VP principle may be applied:
In the early stages of rehabilitation, pay close attention to maintaining range-of-motion exercises for the affected foot but avoid high-intensity kicking movements. If significant pain or discomfort arises during training, stop immediately and seek a follow-up evaluation.
Disclaimer: This report is based solely on the current imaging and clinical information available. The opinions provided are for reference only and cannot replace an in-person consultation or a professional physician’s direct diagnosis and treatment plan. If you have any questions or if symptoms worsen, please seek medical attention promptly.
Freiberg’s disease of the first metatarsal head in a child