Aneurysmal bone cyst of the spine in a 6-year-old boy

Clinical Cases 31.10.2007
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Section: Musculoskeletal system
Case Type: Clinical Cases
Patient: 6 years, male
Authors: Enrique Delgado, Javier Milian, Miguel Baquero, Marina Huguet, Encarna Delgado
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Details
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AI Report

Clinical History

The patient was referred for pain in cervical spine without neurological impairment.

Imaging Findings

The patient presented with pain in cervical spine. No sensory or motor impairment were present at the moment of the admission. He was first evaluated with cervical MRI. We acquired sagital and axial spin-echo T1and T2-weighted sequences. The study showed an expansile cystic lesion in the vertebral body of C3, involving the posterior elements, with internal septation and fluid-fluid levels. We performed a CT scan that showed a lytic lesion and calcified rim with eggshell appearance. The diagnosis of aneurismal bone cyst was proposed.

Discussion

The aneurysmal bone cyst (ABC) is a cystic lesion that may appear in any bone in the body. It most often affects persons during their second decade of life. The ABC is a benign lesion that can be locally aggressive. ABC was first described by Haffe and Lichtenstein in 1942 as “a peculiar blood-containing cyst of large size”. They described two cases in which a lesion with a “soap-bubble” appearance on radiographs was found on the superior pubic ramus of a 17 year-old male and on the second vertebrae of an 18-year-old man. The lesions were expansile and showed evidence of erosion of surrounding bone. Jaffe and Liechtenstein suggested that ABCs may have been mistaken for other benign and malignant bone tumors in the past. Although ABC is a separate entity, in some situations, distinguishing ABC from a giant-cell tumor or telangiectatic osteosarcoma is difficult. As defined by the World Health Organization, the ABC is a benign tumorlike lesion. It is described as "an expanding osteolytic lesion consisting of blood-filled spaces of variable size separated by connective tissue septa containing trabeculae or osteoid tissue and osteoclast giant cells." Although benign, the ABC can be a rapidly growing and destructive bone lesion. The expansile nature of the lesions can cause pain, swelling, deformity, disruption of growth plates, neurologic symptoms (depending on its location), and pathologic fracture. ABCs generally are considered rare, accounting for only 1-6% of all primary bony tumors. Most studies also have found a slightly increased incidence in women. The ABC can appear in persons of any age, but it is generally a disease of the young. Most ABCs, about 50-70%, occur in the second decade of life, with 70-86% occurring in patients younger than 20 years. The mean patient age at onset is 13-17.7 years. ABCs are rare in the very young. Our patient was only 6 years old. Patients usually present with pain, a mass, swelling, a pathologic fracture, or a combination of these symptoms in the affected area. Symptoms are usually present for several weeks to months before the diagnosis is made. The mass may also have a history of rapid enlargement. Neurologic symptoms are typically associated with ABCs in the spine. Pathologic fracture occurs in about 8% of ABCs, but the occurrence rate may be as high as 21% in ABCs with spinal involvement. Other findings may include the following: Deformity. Decreased range of motion, weakness, or stiffness. Reactive torticollis. Warmth over the affected area Radiological diagnosis is based in expansile or cystic bone lesion, with internal septations, calcified rim with eggshape appearance, and fluid-fluid levels, these are most often found in the ABC, but they are not exclusive to it.

Differential Diagnosis List

ANEURYSMAL BONE CYST

Final Diagnosis

ANEURYSMAL BONE CYST

Liscense

Figures

Coronal SE T1

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Coronal SE T1

Coronal DP Fat Sat

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Coronal DP Fat Sat

Axial DP Fat Sat

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Axial DP Fat Sat

Sagital FSE T2 Fat Sat

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Sagital FSE T2 Fat Sat

Axial CT

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Axial CT

CT. Coronal Reconstruction

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CT. Coronal Reconstruction

CT Sagital Reconstruction

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CT Sagital Reconstruction