A 19-year-old male adolescent presented with a swelling of the left knee joint for 2 years with restricted movement for 2 months. There was no history of trauma.
Magnetic Resonance Imaging (MRI) revealed a frond-like intra-articular mixed signal intensity lesion in the anterior aspect of the left knee joint, predominantly hyperintense in T1-weighted image (T1WI), less hyperintense in T2-weighted image (T2WI) and proton density image (PDI). On short T1 inversion recovery (STIR) sequences it showed signal suppression. After intravenous contrast, no appreciable enhancement was noted. There was mild joint effusion.
Lipoma arborescens is one of the rare intra-articular lesions which is caused by inflammation of synovial fluid with deposition of mature fatty components within them. [1, 2] This term was first coined by Hoffa and was elaborated in detail by Arzimanoglu. [3, 4] The Latin term arborescens refers to the leafy appearance of a tree similar to that of a frond. [5] The anterior and superior aspect of the knee is most commonly affected, however, involvement of other appendicular joints is also reported in the literature. [5, 6, 7, 8]
The infiltration of mononuclear cells leads to an inflammatory reaction, causing hypertrophy of the synovium and deposition of mature lipocytes, showing a frond-like appearance. [9]
Magnetic Resonance Imaging (MRI) is the modality of choice for radiological diagnosis of lipoma arborescens. [10] It shows high signal intensity in T1WI, is less hyperintense in T2WI and hypointense on fat-suppressed sequences. [9, 11]
Computed tomography (CT) reveals a non-enhancing, low density, frond-like intra-articular mass. [12]
On ultrasonography (USG) a lobulated hyperechoic mass is seen mostly associated with a variable amount of joint effusion. [13]
Plain X-ray films may demonstrate feathery fatty lucency within a joint with joint effusion and bony erosion. [11]
This condition is usually benign and asymptomatic, however, synovectomy is indicated for patients with persistent pain. [9]
Lipoma arborescens is one of the rare intra-articular benign lesion, characterised by synovial proliferation with frond-like deposition of mature fatty components. MRI is the best radiological diagnostic tool for pre-operative evaluation. Although it is very uncommon, it can be one of the causes of chronic large joint swellings, especially of the knee joint. Synovectomy is indicated for symptomatic patients.
Lipoma arborescens
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MRI images of the patient’s left knee joint show abnormal soft tissue signals with lobulated, frond-like projections within the joint cavity. On T1WI, high-signal areas are visible; on T2WI, the signal is relatively high but slightly lower than T1WI. On fat-suppressed sequences, the signal decreases. Overall, these findings resemble fat signal characteristics. Joint effusion is observed, and no significant bony destruction or marked bone erosion is noted.
These imaging features suggest synovial proliferation and fat deposition within the joint, forming lobulated, frond-like structures, with no obvious calcification or bone destruction.
Given the absence of a significant trauma history, the presence of fat-like signals, and the frond-like synovial proliferation confined to the joint cavity, the findings most closely align with the typical presentation of lipoma arborescens.
Considering the patient’s age, clinical presentation (chronic joint swelling, limited range of motion), and MRI findings (lobulated fatty signals, accompanying joint effusion), the most likely diagnosis is: Lipoma arborescens.
Rehabilitation should follow a gradual, individualized approach (the FITT-VP principle: Frequency, Intensity, Time, Type, Progression, and Volume).
This report is based on the existing imaging and clinical information for a preliminary analysis and is provided for reference only. The specific diagnosis and treatment plan should be determined by a professional physician through an in-person consultation and comprehensive assessment of the patient’s actual condition.
Lipoma arborescens