Compartment syndrome of the fibular nerve after trauma secondary to a ganglion cyst.

Clinical Cases 28.10.2020
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Section: Musculoskeletal system
Case Type: Clinical Cases
Patient: 45 years, female
Authors: Marco Di Serafino1, Rocco Minelli2, Francesca Iacobellis1, Antonio Borzelli1, Roberto Ronza1, Maria Laura Schillirò1, Venere Delli Paoli3, Ciro Acampora1 and Luigia Romano1
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Clinical History

A 45-year-old woman presented to the emergency department with acute right lower extremity paresthesias and tenderness at right fibular head after a previous skiing accident with axial rotation of the lower limb. There was swelling in the area of the fibular head and weakness in foot eversion and dorsiflexion

Imaging Findings

X-ray of the right leg excluded any bone trauma.  Electromyogram was suggestive for fibular nerve’s neuropathy. US was performed to investigate the subcutaneous tissues and muscle planes of the swelling proximal right fibular area, showing at the tibia-fibular proximal recess, an anechoic-fluid and not vascularized fusiform cystic mass with welldefined border of about 16 mm in diameters [Fig.1]. MRI confirmed the US findings also with irregularities of the tibia-fibular articular surface and a relative edema of the fibular bone due to previous indirect torsional trauma.  The mass continued caudally to the anterior-lateral side of the fibular neck with a fusiform morphology along the complementary muscle spaces with a maximum diameter of about 30 mm compressing the deep fibular nerve [Fig. 2]. The diagnosis of fibular nerve palsy was confirmed, and the patient was prescribed a dorsiflexion ankle-foot orthosis for protection and anti-inflammatory therapy before considering a surgical excision.

Discussion

Peripheral neuropathies caused by ganglion cysts are rare, particularly in the lower extremities. Ganglion cysts are the most frequent tumours affecting the upper limbs and rarely cause compression of the peripheral nerves [1]. The ganglion cyst causing neuronal compartment syndrome of the ulnar nerve due to growth in the Guyon canal [2] or the cubital tunnel [3] and the median nerve due to spread in the carpal tunnel [4] has been described in the upper extremity. Compression neuropathies of the lower limbs are much less common and only a few cases have been described in the surgical literature since Sultan's first description of a fibular nerve neuropathy in 1921 [5]. The aetiology of ganglion cysts is not entirely clear, although previous traumas are possible. An electromyogram study may be helpful to correlate clinical findings by distinguishing the extent of sensory and motor impairment. Furthermore US and MRI are validated diagnostic procedure in compartmental nervous syndrome. At US the ganglion cyst has regular border with typical anechoic content and not vascularized at colour-Doppler mode. MRI is usually the technique of choice thanks to the excellent soft tissue contrast with the possibility of multiplanar images reconstruction. It allows to better define the ganglion cystic mass, the extension and any related compressive effects as well as any changes of the bone or muscle structure [6, 7] At MRI ganglia have a characteristically low signal intensity at T1-weighted images and high signal intensity at T2/STIR-weighted images with a peripheral rim enhancement after intravenous administration of gadolinium (8). Currently, the accepted treatment of peroneal nerve palsy due to ganglion cyst is a surgical removal of the mass (9). Decompression is recommended even for patients presenting with only sensory symptoms, if the symptoms have been substantiated by electrophysiological studies. The most common complication of surgical ganglion removal is the local recurrence. Given the rarity of post-traumatic compartment syndrome of the fibular nerve a proper history and physical examination are needed followed by a targeted diagnostic procedure that sees in electromyography and especially in the multimodal diagnostic imaging such as US and MRI the best diagnostic work-up.

Differential Diagnosis List

Compartment syndrome of the fibular nerve after trauma secondary to a ganglion cyst
Ganglion cyst
schwannoma
giant plexiform neurofibromatosis
nerve herniation through a fascial defect
pneumatic compression

Final Diagnosis

Compartment syndrome of the fibular nerve after trauma secondary to a ganglion cyst

Figures

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Ultrasound scans of tibio-fibular proximal recess and fibular nerve area show: an anechoic multi-loculated fusiform mass of a

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Magnetic resonance imaging findings of the ganglion cyst and spatial distribution: hyper-intense FRFSE T2w (yellow arrowheads