Painless mobile tumefaction of ligneous consistency in the left thigh.
Two years previously the patient had noted a painless tumefaction situated close to the left hip, which increased in size rapidly until, at admission, the lesion was extending along the lateral surface of the thigh. The mass was ligneous on palpation, mobile to the superficial tissues and fixed to the deeper tissues.
US imaging revealed a multiloculated mass of size 15 x 10cm with fluid areas inside and hyperechoic septa.
MRI was not carried out because patient was claustrofobic.
CT enhanced images showed a soft tissue mass located at the fascial plane of the fascia lata muscle which extended caudally in the superficial tissue of the thigh. The lesion appeared multiloculated with hypodense areas circumscribed by hyperintense, poorly enhanced septa.
The diagnosis of nodular fasciitis was made after resection of the mass.
Nodular fascitis (NF) is a soft tissue lesion composed of proliferating fibroblasts; the lesion is described as: subcutaneous, pseudosarcomatous fibromatosis, demonstrating an alarming nodular proliferation of fibroblasts [1,2].
Clinically most patients present with a rapidly enlarging, palpable soft tissue mass. Commonly this occurs on the upper extremities (48%), the trunk (20%), head and neck (17%), and lower extremities (15%). NF can be classified into three subtypes, according to its anatomic location: subcutaneous, intramuscular and fascial, which spreads along the superficial fascial tissue [2].
The histological features show immature, not atypic fibroblasts, arranged in characteristic short and irregular bundles.
MRI findings of nodular fascitis are: lesions appear slighty hyperintense to skeletal muscle on T1-weighted images, and hyperintense on T2-weighted images with fat saturation ( either FS or STIR sequences );after intravenous gadolinium administration lesions usually, show homogeneous enhancement[3].
Enhanced CT examination is helpful in investigating the origin and extension of the mass and its connections with surrounding tissues, therefore providing valid diagnostic support for surgery [4,5].
Nodular fascitis
According to the provided contrast-enhanced CT images, a noticeable soft tissue mass with relatively well-defined boundaries is observed in the left thigh. On non-contrast scans, the lesion appears slightly hyperdense or isodense, while post-contrast images show relatively uniform enhancement. No evident adjacent bone destruction or periosteal reaction is seen. The surrounding muscular structures are essentially intact, and no obvious signs of bony invasion are noted at this stage.
Clinically, the patient describes the mass as having a “slightly firm (ligneous consistency), mobile, and painless” nature. The location of the mass and its relatively uniform enhancement suggest the possibility of a benign soft tissue lesion.
Considering the patient’s age (60 years), clinical presentation (a painless, mobile mass in the left thigh), the soft tissue characteristics with relatively well-defined and moderately homogeneous enhancement on imaging, and the fact that nodular fasciitis can appear as “pseudo-sarcomatous” proliferation on imaging—exhibiting rapid growth but still representing a benign process—the most likely diagnosis is Nodular Fasciitis (Nodular Fascitis).
For definitive confirmation, an image-guided core needle biopsy or surgical excision followed by pathological examination may be considered to clarify the nature of the lesion.
Treatment Strategy:
Rehabilitation/Exercise Prescription Suggestions (FITT-VP Principle):
This report provides an academic and reference-based analysis derived from the available clinical history and imaging data. It is not a substitute for in-person medical diagnosis or individualized medical advice. If you have any concerns or experience any changes in symptoms, please seek prompt medical attention or consult a qualified healthcare professional.
Nodular fascitis