Palpable soft-tissue mass of the right leg
The patient consults for a swelling upon the lateral malleolus of the right leg, with neuralgic pain. There was no sensitive or motive deficit. Radiographics were normal. Ultrasonography and MRI of the leg were realized.
Schwannoma is a rare benign neurogenic tumor developing from schwan cells but it is the most common of all peripheral tumours (1, 2). The risk of malignant degeneration in a schwannoma is exceedingly rare. It occurs at all ages but most commonly in persons between the ages of 20 and 50 years and represents approximately 5% of benign soft-tissue neoplasm (3). Men and women are affected equally. Schwannoma of the foot is very rare (3). Most lesions are solitary and present as a slowly growing painless soft-tissue mass (3). On clinical exam, this mass is often mobile in transverse direction (2), but fixed along the nerve; painful paresthesia in the dermatome of the nerve of origin, similar to tinel’s sign may be present (1, 2). Sonography identified the 3-dimensionnal localization of the nerve tumor its origin from a nerve fascicle, and its relationship with non involved nerve fascicles (4). MRI is the best imaging investigation for the diagnosis of schwannoma. On T1-weighted images, schwannomas have intermediate signal intensity similar to that of muscles. Sometimes they are hardly visible. On T2-weighted images schwannomas show markedly increased signal intensity. Cystic lesions within them, which are typically found in schwannomas, show low signal intensity on T1-weighted images and high on T2-weighted. Usually, small schwannomas tend to enhance uniformly after gadolinium whereas larger lesions show a more heterogeneous enhancement. The detection of a capsule on MRI visualized as low intensity rim could be detected in 70% of the schwannomas and in 30% of the neurofibromas (3). The principle of schwannoma surgery is simple enucleation of tumour without damaging the nerve (2, 3). Nerve fibres do not traverse the substance of the schwannoma and operative excision should therefore not compromise nerve function.
Schwannoma of the superficial peroneal nerve
Based on the provided MRI images, a round or oval lesion is observed within the soft tissue of the right lower leg (proximal to the ankle joint / foot and ankle region), showing relatively well-defined margins. On T1-weighted images, the lesion generally exhibits signal intensity that is moderate or slightly lower than that of muscle, with some areas of slightly low signal. On T2-weighted images, the lesion appears as high signal with clear boundaries; some cyst-like low or high signal zones may be present internally. It is clearly demarcated from surrounding tissues, and a capsule-like low signal ring may be seen on certain sequences. Located near the course of a nerve with a round or oval shape, its overall appearance is consistent with a typical schwannoma (Schwannoma).
Considering the imaging features, the patient's gender and age (49-year-old female), the slow-growing, palpable nature of the mass, and the typical MRI presentation with clear margins and correlation to the nerve pathway, the most likely diagnosis is Schwannoma.
In cases with atypical signs or high suspicion of malignancy, further confirmation via histopathological biopsy or intraoperative frozen section is recommended.
The main goals of postoperative rehabilitation include:
Planning rehabilitation under the FITT-VP principle (Frequency, Intensity, Time, Type, and Progression):
Throughout rehabilitation, closely monitor surgical site pain, swelling, and neurological function. Any significant deterioration or anomalies require prompt reevaluation and adjustment of the rehabilitation plan.
This report provides a reference-based analysis rooted in the supplied information and does not replace in-person medical evaluation or professional healthcare advice. The definitive diagnosis and treatment planning should be determined by qualified medical professionals, taking into account the patient’s full medical history, physical examination findings, and other auxiliary test results.
Schwannoma of the superficial peroneal nerve