Forestier’s disease

Clinical Cases 28.05.2006
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Section: Musculoskeletal system
Case Type: Clinical Cases
Patient: 72 years, male
Authors: Authors: Rajagopal S, Pfleiderer A G.
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AI Report

Clinical History

A 72-year-old male presenting with mild throat discomfort with a prominent bony hard swelling on the posterior pharyngeal wall that was found to be due to florid osteophyte formation involving the anterior cervical spine.

Imaging Findings

A 72- year-old male presented to the ENT department with complaints of throat discomfort. There was no associated dysphagia, respiratory symptoms or complaints of neck stiffness or pain. He was a diet controlled diabetic, and on treatment for hypertension and hypercholestrolemia. The only abnormality found on ENT examination was a marked smooth bony protuberance in the midline on the posterior oro-pharyngeal wall. A lateral cervical spine radiograph showed a ‘flowing’ ossification along the anterior margins of the cervical vertebrae extending from C2 to C6.

Discussion

Diffuse Idiopathic Skeletal Hyperostosis (DISH) or Forestier’s Disease is a non- inflammatory skeletal disease characterised by the ligamentous calcification of the anterolateral spine. It has marked predilection for the axial skeleton, but can involve peripheral sites such as the peripatellar ligaments, the Achilles tendon insertion, plantar fascia and olecranon.   Thoracic involvement is most common and occurs in 99% of cases, while cervical involvement occurs in 75%. It is more common and severe in men than women. However the aetiology remains unknown but hyperinsulinemia with or without diabetes, obesity, hyperuricemia, dyslipidemia, hypertension, coronary artery disease and the prolonged use of isoretinol are considered to be significant risk factors.   Patients with DISH are usually asymptomatic but can present with neck stiffness and pain, dysphagia, hoarseness, foreign body sensation or even stridor (3).   The diagnosis is made solely on the radiographic appearances and abnormalities using the criteria described by Resnick and Niwayama(2) which are a) the presence of flowing calcification and ossification along the anterolateral aspect of at least four contiguous vertebral bodies with or without associated localised pointed excrescence at the intervening vertebral body-disc junctions b)a relative preservation of intervertebral disc height of the involved vertebral segments and the absence of extensive radiographic changes of degenerative disc disease, including the vacuum phenomenon and vertebral body marginal sclerosis and c) the absence of apophyseal joint bony ankylosis and sacro-iliac joint erosion, sclerosis or bony fusion.   The treatment of DISH is essentially conservative and surgical removal of hyperostosis is only considered if symptoms are significant.

Differential Diagnosis List

Diffuse Idiopathic Skeletal Hyperostosis (DISH) (Forestier’s Disease)

Final Diagnosis

Diffuse Idiopathic Skeletal Hyperostosis (DISH) (Forestier’s Disease)

Liscense

Figures

lateral radiograph of neck showing flowing osteophytes

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lateral radiograph of neck showing flowing osteophytes